Sploder

The Sploder is a variation of the Afflicted encountered by Claire Redfield and Moira Burton in Resident Evil Revelations 2. Sometimes, when an Afflicted is killed, it will undergo a secondary mutation, developing bubbling pustules that completely envelop the upper body. The new creature lacks a visible head and any obvious sensory organs, so it is unclear how it tracks its targets, though it likely senses motion somehow.

Behaviour
The Sploder will relentlessly advance on its prey at a steady pace. When it gets close enough, its body will fill with acidic bile and pus, causing its bloated form to visibly expand and violently explode. The acidic fluids released by the Sploder can cause serious injury or temporarily blind the player. There is a brief window of opportunity for one to get to a safe distance before the creature explodes and avoid damage altogether.

Weaknesses
Sploders have very little health and any damage they sustain causes their pustules to expand to a certain degree. Shooting them is a waste of ammunition, however, since exposure to light has the same effect. Shining a flashlight on a Sploder will cause its boils to erupt before it can get too close. Alternatively, if the creature does get in close, it is entirely possible to run out of the way before the creature detonates.