Thrax

Thrax is the main antagonist of the Warner Bros. animated/live-action film Osmosis Jones. He is a virulent, contagious and malicious anthropomorphic fictional virus that reaches the body of Frank Detorre thanks to the fact that he ate an egg infected by the saliva of a chimpanzee. Being inside it, he sets out to kill Frank in less than 48 hours to set his record as the deadliest virus ever existed.

Appearance
Thrax has a humanoid appearance with a dark shade of red. He wears completely black, consisting mainly of a trench coat and long pants. He has hands with long fingers that appear to be claws. Unlike the other germs, Thrax has a more monstrous and sinister appearance.

Personality
At first glance, Thrax seems to be a polite and sophisticated individual, but in reality he is a very horrendous guy. He is an extremely dark and threatening villain that contrasts directly with the comedic and light-hearted tone of the movie. As a serial killer, he lives of causing the death of his hosts in the fewest time possible. He is very sadistic, greatly taking pleasure in killing and causing pain to both cells and humans alike. He often brags with his victimis with a dark and macabre sense of humor.

He always keeps a chain of DNA of all of his victims as a creepy and terrifying keepsake and often singsongs Peggy Lee's "fever" song whenever he is spreading his diseasy as a twisted sense of irony.

While having a certain degree of charisma, he is also temperamental and volatile, as he is easily offended by negative comments either towards himself or when his plan is often questioned. He dislikes being compared to other viruses such as Ebola, as he considers them to be a simple "cold". Despite his violent tendencies, Thrax has proven to be intelligent, meticulous, calculating and very knowledgeable about human anatomy, knowing how to camouflage himself among other viruses, get rid of the traces of his actions, and where to attack as efficiently as possible.

Abilities
Thrax is a very lethal virus that is capable of disintegrating any cell or anything it encounters with just a touch of its index claw. When it touches its victim, it turns red in a few seconds swelling and later explodes causing its death. He is also a very efficient hand to hand combatant, shown when he was able to fight Ozzy in his final battle in Shane's eye. He is extremely intelligent, having absolute knowledge about human anatomy, which he takes advantage of to infiltrate the most recondite place possible and thus be able to infect the victim.

Biography
In the beginning of the story, Thrax enters the body of Frank DeTorre, a widower without the slightest regard for hygiene and health, when the latter eats an egg that was just spit by a monkey into a muddy floor. By doing so, he infiltrates Frank City, a huge metropolis inside Frank's body in which each of his body cells are living a life identical to that of humans, with white blood cells as cops and germs as criminals.

Thrax casually murders the two witnesses of his arrival, and goes to the germs headquarters in Frank's armpit. There, he quickly takes control of the germs gangs by killing their leader; and plans to take advantage of Frank's poor health condition to operate undetected.

The titular primary protagonist is Osmosis "Ozzy" Jones, one of Frank's white blood cells who was demoted from the police after he activated the emergency evacuation (i.e. throwing up), to get rid of germs from polluted oysters, which was seen as "unnecessary force".

He gets reluctantly teamed up with a rule abiding cold pill named Drix (Drixenol) to investigate on a throat inflammation (in fact Thrax's doing), and they discover that something far more dangerous is going on. However, the incompetent and election-obsessed Mayor Phlegmming, who is to blame for Frank's disastrous life-style, dismisses their warnings and states that this is nothing more than a "common cold".

Jones uses his body-altering abilities to pass as a germ and infiltrates a meeting of Thrax and his thugs inside a zit, to get in on what is going on. There, he discovers about Thrax's plan to set a record with Frank's death. When Ozzy is caught, Drix barges him just as Thrax was about to incinerate him. After a brief battle, the zit is destroyed in the explosion of a medicine grenade, killing most of Thrax's gang and seemingly Thrax himself as well.

Yet, the virus has survived and is hiding in a toenail with his remaining thugs. As Thrax prepares to get back on schedule, one of his gangsters suggest they incubate for a while as they are few in numbers (which would mean he won't be able to break his record). Angered and disillusioned, Thrax kills his remaining mobsters in an explosion, heading off to finish things as a lone wolf.

Phlegmming fires both Ozzy and Drix, but they keep investigating nonetheless, until they can be sure that Thrax is really gone. They go to the memory zone of the brain and discover that Thrax has sneaked in. Meanwhile, Leah Estrogen, the mayor's assistant and Ozzy's love interest, starts suspecting that something is amiss, but even when he can no longer ignore the situation, Phlegmming keeps underestimating it. Leah starts her own investigation in the brain and stumbles upon Thrax, who stole a DNA bead from Frank's hypothalamus, causing his body temperature to skyrocket, and the entire city to be devastated in a fire, under Phlegmming's disbelieving and remorseful eyes.

Despite her activating the alarm and putting up quite a fight, Thrax takes her as a hostage to force Ozzy and Drix, who caught up with them, to let him go, but not before Drix could shoot Thrax’s claw with a freezing blast, preventing him from using it.

As Frank is being rushed into the hospital in critical condition, Thrax triggers a sneeze to exit his body, followed by Ozzy who used Drix's cannon to propel himself after his foe, landing in Frank's daughter Shane's eye.

Ozzy and Thrax engage a fistfight, with Ozzy altering his body structure to better fight his foe, fighting him evenly. Thrax manages to catch Ozzy and strangles him with the DNA chain, gloating that he will break his record with Shane as soon as Frank dies, but Ozzie traps him on the girl's fake eyelash that is about to fall.

Ozzy clings to Shane's real eyelash, with the DNA chain still around his neck, while Thrax falls into a bottle of rubbing alcohol and dissolves to death. Ozzy then uses Shane's teardrop to re-enter Frank's body and replace the stolen DNA, saving Frank's live in extremis.

As Frank is saved and vows to adopt a healthier life-style, Phlegmming is impeached and fired, and Ozzy is appointed as an elite cop, with Drix as his partner and Leah as his girlfriend.